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Results for COVID-19|UVic MRMAssayDB

You searched for: COVID-19


The proteomics community possesses a large and increasing amount of knowledge on precise and reproducible targeted assays, but these assays are not yet utilized to their full potential, particularly for clinical applications. Currently, MRMAssayDB lists validated assays for 1553 surrogate peptide assays that can be used to quantify 60 proteins. Using MRMAssayDB, an integrative resource on targeted proteomics assays, we have data-mined all of the available MRM assays to determine which ones can be used for these COVID-19. Because MRMAssayDB links all assays to DrugBank and other knowledge bases, and to protein-protein interactions, it enables straight-forward design of multiplexed MRM assays for studying the pathways and interactions that involve these COVID-19.


UniProtKB Accession Protein Gene Organism Subcellular localization Stripped Peptide Sequence Modified Peptide Sequence Peptide unique in proteome Peptide present in isoforms PeptideTracker ID PeptideTracker Transitions PASSEL ID PASSEL Transitions SRMAtlas ID SRMAtlas Transitions CPTAC ID CPTAC Transitions PanoramaWeb ID PanoramaWeb Transitions Number of repositories Best Transitions Biological Pathway Protein–protein interaction Disease Association 3D structure GO Terms Drug Association Protein approved as FDA Marker Mean Concentration
UniProtKB Accession Protein Gene Organism Subcellular localization Stripped Peptide Sequence Modified Peptide Sequence Peptide unique in proteome Peptide present in isoforms PeptideTracker ID PeptideTracker Transitions PASSEL ID PASSEL Transitions SRMAtlas ID SRMAtlas Transitions CPTAC ID CPTAC Transitions PanoramaWeb ID PanoramaWeb Transitions Number of repositories Best Transitions Biological Pathway Protein–protein interaction Disease Association 3D structure GO Terms Drug Association Protein approved as FDA Marker Mean Concentration

Summary of results


The number of peptides entries in MRMAssayDB, sorted by organism
Species Name Number of assays Number of covered proteins
Homo sapiens 1553 60
Total 1553 60
Uniqueness and presence in isofroms
Database name Peptide uniqueness in proteome(%) Peptide is specific to one protein isoform(%)
PeptideTracker 95.0% 0.0%
PASSEL 97.1% 0.0%
SRMAtlas 94.26% 0.0%
CPTAC 100.0% 0.0%
PanoramaWeb 90.57% 0.0%
The number of peptides entries in MRMAssayDB, sorted by sub cellular location (Top50)
Sub cellular location Number of unique entries(Proteins)
Cytoplasm 31
Cell membrane 29
Secreted 19
Nucleus 17
Endosome 13
Lysosome 10
Late endosome 9
Golgi apparatus 8
Endoplasmic reticulum membrane 8
Endosome membrane 8
Cytoplasmic vesicle 7
Mitochondrion 7
Lysosome membrane 5
Late endosome membrane 5
Cell projection 5
Apical cell membrane 4
Early endosome 4
Endoplasmic reticulum-Golgi intermediate compartment 3
Golgi apparatus membrane 3
Melanosome 2
Lipid droplet 2
Early endosome membrane 2
Mitochondrion inner membrane 2
Cell junction 2
Smooth endoplasmic reticulum membrane 1
Perikaryon 1
Mitochondrion membrane 1
Basolateral cell membrane 1
Endomembrane system 1
Cytoplasmic granule 1
Melanosome membrane 1
Photoreceptor inner segment 1
Membrane raft 1
Mitochondrion outer membrane 1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1
Nucleus speckle 1
Inflammasome 1
Chromosome 1
The number of peptides entries in MRMAssayDB, sorted by GO term name (Top50)
GO Term Name Number of unique entries(Proteins)
protein threonine kinase activity 3
Golgi apparatus 7
lysosome 11
nucleoplasm 13
RNA binding 11
double-stranded RNA binding 5
identical protein binding 15
zinc ion binding 7
intracellular membrane-bounded organelle 5
positive regulation of interferon-alpha production 7
early endosome 12
mitochondrion 9
cell surface 19
positive regulation of transcription, DNA-templated 8
plasma membrane 38
extracellular space 18
extracellular region 17
cytosol 25
ATP binding 8
cytoplasm 25
extracellular exosome 23
late endosome 8
phagocytic vesicle membrane 6
innate immune response 22
integral component of plasma membrane 11
positive regulation of interleukin-6 production 12
protein serine kinase activity 3
viral process 17
lysosomal membrane 9
nucleus 20
positive regulation of interferon-beta production 10
defense response to virus 15
membrane 50
response to virus 18
positive regulation of gene expression 7
membrane raft 5
cytokine-mediated signaling pathway 10
protein kinase binding 8
positive regulation of transcription by RNA polymerase II 12
inflammatory response 21
signal transduction 11
Golgi membrane 10
endosome membrane 15
late endosome membrane 6
positive regulation of I-kappaB kinase/NF-kappaB signaling 7
type I interferon signaling pathway 9
positive regulation of tumor necrosis factor production 7
positive regulation of ERK1 and ERK2 cascade 6
integral component of membrane 13
neutrophil degranulation 10

Pathway coverage (Top 10)


Distribution of proteins and peptides among different databases.

      Unique Proteins



      Unique Peptides